If you use miles as a unit of length than - the distance from Rancho Santa Margarita to Winston-Salem is two thousand, four hundred and forty-three miles.
The road trip out of Rancho Santa Margarita to Winston-Salem will take approximately one day eleven hours twenty-five minutes if you drive with average speed and the absence of accidents and traffic jams
Watch distance between Rancho Santa Margarita and Winston-Salem
Flight from Rancho Santa Margarita to Winston-Salem