If you use miles as a unit of length than - the distance from Lexington-Fayette to Cape Girardeau is zero miles.
The road trip out of Lexington-Fayette to Cape Girardeau will take approximately if you drive with average speed and the absence of accidents and traffic jams
Watch distance between Lexington-Fayette and Cape Girardeau
Flight from Lexington-Fayette to Cape Girardeau